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Tobacco Smoking and E-Cig Vaping in Worsening of Other Neurological Diseases and Nicotine-CNS Drug Interactions Alzheimers Disease Alzheimers disease (AD) is the most common cause of elderly-age dementia and is characterized by the accumulation of amyloid- (A) protein in extracellular senile plaques and neurofibrillary tangles due to intraneuronal tau deposition (Mucke 2009)

Canadian Medical Association Journal

In the 1930s and 1940s smoking became wildly popular, however, in the 1950s questions started to arise about smokers contracting illnesses and dying younger than non-smokers